SPIDR Outputs

Zhang, P., Walko, M., Wilson, A.J., (2023) Maleimide constrained BAD BH3 domain peptides as BCL-xL Inhibitors: A Versatile Approach to Rapidly Identify Sites Compatible with Peptide Constraining. Bioorg. Med. Chem. Lett., 87, 129260.

Arter, C., Trask, L., Ward, S., Yeoh, S., Bayliss, R (2022) Structural features of the protein kinase domain and targeted binding by small-molecule inhibitors. J Biol Chem. 298(8) DOI: 10.1016/j.jbc.2022.102247

Zhang, P., Walko, M., & Wilson, A.J., (2023) Rational Design of Harakiri (HRK)-Derived Constrained Peptides as BCL-xL inhibitors. Chem. Commun., DOI: 10.1039/D2CC06029A

Batchelor, M., Dawber, R.S., Wilson, A.J., & Bayliss, R. (2022) α-Helix stabilization by co-operative side chain charge-reinforced interactions to phosphoserine in a basic kinase-substrate motif. Biochem J, 479 (5), 687–700