Structures and Probes of Intrinsically Disordered Regions
Amy Rees SPiDR’s Jack Roberts will be talking at Pint of Science on 13 May about the role of protein disorder in health and disease.
The theme of the evening is ‘From Bench to Bedside’. Join Jack and the others for what promises to be an enlightening discussion.
Over the summer holidays, Jennifer Miles, Matt Batchelor and Isha Mohan hosted two sixth form students on the In2Science scheme in the School of Molecular and Cellular Biology.
The students were introduced to numerous techniques that are used daily on the SPIDR project and given hands on experience in protein crystallisation.
On a beautifully sunny day in June, Jennifer Miles got on her soapbox to present her research to members of the general public in York with a talk, ‘Seeing Small: Studying the ‘toolkit’ inside our bodies’.
Jennifer’s aim was to present some of the techniques we use on the SPIDR project and why we do them, and to promote structural biology and women in STEM.
Soapbox Science is a novel public outreach platform for promoting women and non-binary scientists and the science they do.
Andy Wilson visited Notre Dame 6th form College in Leeds to give a talk to their lower sixth students about his career.
During his visit, Andy outlined the drug discovery process and explained the important role that chemists play in this process. Andy highlighted the particular challenges associated with discovering new medicines for targets such as protein-protein interactions (PPIs), which typically involve intrinsically disordered domains. Addressing such challenges could translate into potential treatments for major societal diseases. Andy used the PoPPI protein matchmaking game to highlight the complexity of protein-protein interactions.
Head of Department for Chemistry and Physics Rachel Hodgetts said, “Our students really enjoyed learning about the interactions involved in certain drugs and could relate it to their study of intermolecular forces.”
https://www.notredamecoll.ac.uk/news/chemists-key-disease-treatment-students-discover
On 9th February, Jennifer Miles gave a talk on ‘Identification, Characterisation and Inhibition of Protein-Protein Interactions’ at the School of Molecular and Cellular Biology (SMCB) Seminar.
Rob Dawber gave the talk ‘Investigating key protein-protein interactions of the Aurora-A Kinase’ at the BACR & RSC CBBG meeting on 2 December 2021. This virtual meeting was a joint event between the RSC Chemical Biology and Bioorganic Chemistry (CBBG) group and the British Association for Cancer Research (BACR). The aim of the meeting was to bring together two communities with a mutual interest in advancing knowledge in chemical biology as applied to cancer research.
Rob is a final-year PhD student supervised by Andy Wilson and Richard Bayliss.
It is with great pleasure that we invite you to attend “Deciphering the function of intrinsically disordered protein regions: new horizons’ – an interactive, online webinar that will take place (via Zoom) on Friday 4th June, 14.00-17.00 GMT. A series of short pre-recorded talks will be available from Thursday 3rd June for registered attendees to view before the meeting.